Saint-Jean-Baptiste-and-Saint-Etienne has the rank of cathedral and primatiale: the archbishop of Lyon has the title of Primate of Gaul. The construction of the cathedral stretches over three centuries, from 1175 to 1480. The primatiale is classified historical monument since 1862, and is a World Heritage because of its location in the historic site of Lyon.
The Saint George Sanctuary is a neo-Gothic church founded in 1844-1845. The building was built on the site of an old church of the 6th century.
The Saint-Nizier church is one of the most important places of worship in Lyon, both for its antiquity and its architecture. Entirely rebuilt in the 14th and 15th centuries in a flamboyant Gothic style, the church has been a listed building since 1840.