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The Basilica di Santa Maria del Santo Spirito was built in the Renaissance style on the ruins of a 13th-century Augustinian convent, destroyed by fire in 1471. Filippo Brunelleschi drew the plans around 1444, two years before his death in 1446. The plans were reworked and the work undertaken by Antonio Manetti, Giovanni da Gaiole and Salvi d'Andrea, the latter also being responsible for the construction of the dome (1479-1482) with Il Cronaca. The bell tower is the work of Baccio d'Agnolo (1503). The current appearance of the façade is due to an 18th-century plastering that covered the paintings on the pilasters and cornices.

The Basilica of Santo Stefano is a complex of seven churches, the oldest, the Church of Saints Vitale and Agricola, being built from the fourth century. Partly destroyed in the 10th century, the complex was repaired by Benedictine monks in the 11th century.

The basilica of Sant'Ambrogio is one of the oldest churches in Milan, being built between 379 and 386. It is traditionally considered the second most important church in the city of Milan.

The Basilica of Sant'Eustorgio was probably founded around AD 344. According to tradition, Sant'Eustorgio built the church to house the tombs of the three magi.

The Basilica of Superga, built between 1717 and 1731, was commissioned by King Vittorio Amedeo II to celebrate a victory over the French during the War of Spanish Succession.

The Basilica of Maria Santissima del Soccorso was founded in 1108 by Juliet the Norman, daughter of Count Roger. From the original structure, the powerful apses facing east and the powerful 15th-century Gothic arches remain. The temple was rebuilt between 1656 and 1686 to a design by Michele Blasco.

The Basilica of St Anthony of Padua, built between 1238 and 1310, is one of the largest churches in the world and is visited annually by more than 6.5 million pilgrims. In a heterogeneous style (Romanesque, Byzantine, Gothic), the building houses the relics of Saint Anthony of Padua and his tomb.

The Basilica of Saints Boniface and Alexis was built between the 4th and 5th centuries. In 1216, Pope Honorius III (1216-1227) ordered the reconstruction of the complex; the restoration of 1582 was followed by the reconstruction of Tommaso De Marchis in the 1750s and the reconstruction by Somaschi from 1852 to 1860. The modern church retains elements from all these periods. The bell tower is Romanesque, some columns from the church of Honorius are present in the eastern apse of the modern church, the portico is medieval; the 16th-century façade, reworked by De Marchis, highlights the medieval portico.

The Basilica of Saints John and Paul was first erected in 398. This original church was damaged during the sack of Rome (410), then by an earthquake in 442 and was finally sacked by the Normans in 1084. The building was continually remodelled from the 11th century onwards and the building had its present appearance in 1951 when Cardinal Franz Joseph Spellman had its early Christian façade restored.

The Basilica of Saints Sylvester and Martin ai Monti was founded by Sylvester I (314-335) and the preparatory meeting for the first Council of Nicaea was held there in 324. In 500, 772 and 845 the church was rebuilt. The structure of the present church, modified by Filippo Gagliardi in the 17th century, takes up that of the old church and many parts were reused. The church was entrusted for centuries to the Carmelite monks of the ancient observance.