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Constructed in 1116, this church is one of the most important examples of the romanesque style on the Island of Sardinia. It is constructed of local black basalt and white limestone, creating a striped appearance.

The Basilica of St. Camillus de Lellis was built at the request of Pope Pius X (1903-1914) on the project of the architect Tullio Passarelli. Construction began in 1906. Consecrated as a church and erected as a parish in 1910, it was entrusted to regular clerics, the Camillians. The basilica is in neo-Romanesque style with Gothic influences.

The basilica of San Domenico was first consecrated in 1238 by Dominican fathers. During the sacking of 1528, the church and the adjoining conventual building were razed to the ground. In the mid-16th century, the former Templar church of Santa Maria Maddalena was taken over and renovated by the Dominicans, and the construction of the convent began. The church was enlarged at the beginning of the 18th century and was given a new high altar, built by Luigi della Marra.

The church of St. Francis is mentioned as early as the end of the 13th century, although it has 14th-century forms and features. The horizontally crowned façade has an oculus and a striking Gothic portal with a lunette containing a group of terracotta statues of the Virgin and Child enthroned, flanked by two adoring angels.

The Basilica di San Francesco is a 13th century Bolognese church dedicated to St. Francis of Assisi, owned by the Order of Friars Minor Conventual. Between 1397 and 1402, a new large bell tower was erected on a project by Antonio di Vincenzo. After the arrival of the French (1796), the church was deconsecrated and reduced to a customs house. Between 1886 and 1906, Alfonso Rubbiani supervised a restoration that returned the church to its original appearance but with a heavy rebuilding. The bombings of the Second World War caused further damage and collapse of the complex (facade, vaults and cloister), which was then restored.

The Basilica of San Francesco was built between 1228 and 1255. It was enlarged around 1326 and in the 15th century, gradually transforming the Romanesque building into its present Gothic structure. A fire in 1655 destroyed much of the basilica's artwork. The interior was heavily modified in the 19th century.

The Basilica of San Gennaro fuori le mura was built near the catacombs of San Gennaro in the 5th century. The ancient structure is probably the result of the fusion of two ancient cemetery sites, one from the 2nd century containing the remains of Agrippinus of Naples (the first patron saint of the city) and the other from the 4th century, which housed the remains of St. Gennaro, at least until the remains were transferred in the first half of the 9th century. The building underwent transformations between the 9th and 15th centuries, while in the 17th century it was updated according to Baroque trends, becoming first a hospital for plague victims and then a hospice for the poor.

The Basilica of San Giacomo Maggiore was founded in 1267 as a church of the Augustinian order. In the 19th century, the Augustinians gradually abandoned the convent of San Giacomo.

The church of San Giacomo Maggiore was built between 1267 and 1315 by the hermits of Saint Augustine. The church was definitively consecrated in 1344, after the construction of the apse. Between 1483 and 1498, the interior was remodelled: the roof was replaced by a dome supported by three vaults and new chapels. With the suppression of religious orders under Napoleon, the Augustinians were expelled. They returned in 1824 and left the convent of San Giacomo Maggiore in 1860, but continued to occupy the church.

The Basilica of St John the Baptist was built between 1609 and 1646. The bell tower, however, dates from the period between 1400 and 1418 and is the oldest part of the present building. The imposing façade consists of a lower order of twin Ionic pilasters, a portico with pediment with bronze bas-reliefs representing the life of St. John the Baptist (by Enrico Astori of 1908) and statues of St. Ambrose. The upper part of the façade was created between 1699 and 1701 by Domenico Valmagini, who gave it an oval window, a pediment, the statues of St. Peter, St. Paul and four prophets and the central statue of St. John the Baptist (by Siro Zanelli), which represents the highest point of the façade.